Standard Operating Procedure For Sanitation Of Pipes Carrying Distilled Water

by Pharmadocx Consultants


To implement & lay down procedure for  cleaning & sanitization of pipes carrying  distilled water .

RESPONSIBILITY  :  Production Chemist



  1. The storage vessels / pipes are thoroughly cleaned with nylon scrubber form outside .
  • Prepare 3000 liters of 0.1 % w/v solution of Potassium permanganate and transfer it into the storage tank .
  • Open the respective  outlets of D.M water at different locations & let it flow for about 5 minutes .
  •  Close these outlets and reopen them after 30 minutes .
  • Let all the peramanganate solution drain though these outlets till the storage tank gets emptied .

6.Close the outlets

7.Rinse the storage tank with fresh D.M water till it is free from traces of Potassium Permanganate .

( Note : Even 1 ppm of Potassium  Permanganate imparts pinkish colour in water . )

8.Pass the D.M water in the storage tank through on line U.V disinfectant system & rinse the pipe line with it till it is free from trace of Potassium .

Send the sample to check for absence of traces of Potassium Permanganate and on the written approval from Q.C. water should released for use .

Author: (GM Production)Checked by: (QA Manager)Authorised by: (Director Technical)
Date:Date :Date :

                         (Review date on or before 12 months from date of authorization)

Written by Anmol Singh

Anmol Singh Completed his Bachelors in Field of Mechanical and Automation Engineering. He has over 2 Years of experience in field of Pharmaceuticals, Medical Devices, Cosmetics Manufacturing.

11 June 2023

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