Standard Operating Procedure Fortube Filling, Crimping & Batch Coding

by Pharmadocx Consultants

PURPOSE:  To lay down procedure for tube filling, crimping & batch coding.


  1. Q. A. Chemist
  2. Production Manager.

PROCEDURE :-      

A)        Tube Filling :- Load clean tubes in the filling  trays  fill the hopper of filling machine with

cream and cover it. Fit filling nozzle of appropriate size , set fill weight as per requirement . Run the machine for 2 minutes but do not fill the cream in the  tubes. After 2 minutes check  average weight per stroke .Adjust if necessary.

B)        Crimping :-    Crimp  each tube , check the finishing of crimped tubes regularly  & also

ensure that tubes don’t get pressurized during crimping.

C)        Batch Coding :- Set  the batch  no, print it on the tube and cross check with the BPR . The

print must be clear.

Author: (Production Manager)Checked by: (QA Manager)Authorized by: (Director Administration)
Date:Date :Date :

                         (Review date on or before 12 months from date of authorization)

Written by Anmol Singh

Anmol Singh Completed his Bachelors in Field of Mechanical and Automation Engineering. He has over 2 Years of experience in field of Pharmaceuticals, Medical Devices, Cosmetics Manufacturing.

15 June 2023

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