Standard Operating Procedure  For Sanitation Of Pipes Carrying Distilled Water

by Pharmadocx Consultants

PURPOSE:  To implement & lay down procedure for  cleaning & sanitization of pipes carrying  distilled water .

RESPONSIBILITY  :  Production Chemist



  1. The storage vessels / pipes are thoroughly cleaned with nylon scrubber form outside .
  2. Prepare 3000 liters of 0.1 % w/v solution of Potassium permanganate and transfer it into the storage tank .
  3. Open the respective  outlets of D.M water at different locations & let it flow for about 5 minutes .
  4. Close these outlets and reopen them after 30 minutes .
  5. Let all the peramanganate solution drain though these outlets till the storage tank gets emptied
  6. Close the outlets
  7. Rinse the storage tank with fresh D.M water till it is free from traces of Potassium Permanganate.

(Note : Even 1 ppm of Potassium  Permanganate imparts pinkish colour in water . )

8.Pass the D.M water in the storage tank through on line U.V disinfectant system & rinse the pipe line with it till it is free from trace of Potassium .

Send the sample to check for absence of traces of Potassium Permanganate and on the written approval from Q.C. water should released for use .

Author: (GM Production)Checked by: (QA Manager)Authorised by: (Director Technical)
Date:Date :Date :

                         (Review date on or before 12 months from date of authorization)

    Written by Anmol Singh

    Anmol Singh Completed his Bachelors in Field of Mechanical and Automation Engineering. He has over 2 Years of experience in field of Pharmaceuticals, Medical Devices, Cosmetics Manufacturing.

    13 June 2023

    You May Also Like…


    Submit a Comment

    Your email address will not be published. Required fields are marked *

    You cannot copy content of this page

    Open chat
    Contact Us!
    Chat with Us on WhatsApp! We reply within 5 minutes!