Standard Operating Procedure Procedure  For Sanitation Of Pipes Carrying Distilled Water

by Pharmadocx Consultants


To implement & lay down procedure for  cleaning & sanitization of pipes carrying  distilled water .


Production Chemist



  1. The storage vessels / pipes are thoroughly cleaned with nylon scrubber form outside .
  2. Prepare 3000 liters of 0.1 % w/v solution of Potassium permanganate and transfer it into the storage tank .
  3. Open the respective  outlets of D.M water at different locations & let it flow for about 5 minutes .
  4.  Close these outlets and reopen them after 30 minutes .
  5. Let all the peramanganate solution drain though these outlets till the storage tank gets emptied .
  6. Close the outlets
  7. Rinse the storage tank with fresh D.M water till it is free from traces of Potassium Permanganate.

( Note : Even 1 ppm of Potassium  Permanganate imparts pinkish colour in water . )

08.Pass the D.M water in the storage tank through on line U.V disinfectant system & rinse the pipe line with it till it is free from trace of Potassium .

09. Send the sample to check for absence of traces of Potassium Permanganate and on the written approval from Q.C. water should released for use .

    Author: (GM Production)Checked by: (QA Manager)Authorised by: (Director Technical)
    Date:Date :Date :

                             (Review date on or before 12 months from date of authorization)

    Written by Anmol Singh

    Anmol Singh Completed his Bachelors in Field of Mechanical and Automation Engineering. He has over 2 Years of experience in field of Pharmaceuticals, Medical Devices, Cosmetics Manufacturing.

    16 June 2023

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